Myoclonus of peripheral origin: Two case reports
Identifieur interne : 002195 ( Main/Exploration ); précédent : 002194; suivant : 002196Myoclonus of peripheral origin: Two case reports
Auteurs : Louise Tyvaert [France] ; Pierre Krystkowiak [France] ; Francois Cassim [France] ; Elise Houdayer [France] ; Alexandre Kreisler [France] ; Alain Destée [France] ; Luc Defebvre [France]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-01-30.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adolescent, Amputation Stumps (physiopathology), Anterior Horn Cells (physiology), Anti-Dyskinesia Agents (therapeutic use), Arm Injuries (surgery), Botulinum Toxins, Type A (therapeutic use), Brachial Plexus (injuries), Brachial Plexus (physiopathology), Case study, Cervical Vertebrae, Cicatrix (physiopathology), Elbow (injuries), Electromyography, Female, Humans, Lidocaine (therapeutic use), Male, Middle Aged, Myoclonus, Myoclonus (drug therapy), Myoclonus (etiology), Nervous system diseases, Neural Conduction, Pain, Paresthesia (etiology), Phantom Limb (complications), Phantom limb, Physical Stimulation (adverse effects), Spinal Osteophytosis (complications), Ulnar Nerve (injuries), Ulnar Nerve (physiopathology), nerve injury, peripheral myoclonus, phantom‐limb pain, spinal myoclonus.
- MESH :
- chemical , therapeutic use : Anti-Dyskinesia Agents, Botulinum Toxins, Type A, Lidocaine.
- adverse effects : Physical Stimulation.
- complications : Phantom Limb, Spinal Osteophytosis.
- drug therapy : Myoclonus.
- etiology : Myoclonus, Paresthesia.
- injuries : Brachial Plexus, Elbow, Ulnar Nerve.
- physiology : Anterior Horn Cells.
- physiopathology : Amputation Stumps, Brachial Plexus, Cicatrix, Ulnar Nerve.
- surgery : Arm Injuries.
- Adolescent, Cervical Vertebrae, Electromyography, Female, Humans, Male, Middle Aged, Neural Conduction.
Abstract
The concept of peripheral myoclonus is not yet fully accepted by the medical community because of the difficulty in establishing a cause‐and‐effect relationship between trauma and subsequent movement disorders. Here, we report two cases of patients suffering from peripheral myoclonus after nerve injury. The first patient experienced myoclonus of the 4th dorsal interosseous muscle several days after trauma to the elbow. The second patient presented myoclonus of the arm stump (combined with phantom‐limb pain) 1 year after amputation. In both cases, central nervous system function (spine and brain imaging, somesthetic evoked potentials, EEG back‐averaging) was normal. For the second patient, local infiltration of xylocaine and botulinum toxin into the stump scar rapidly stopped myoclonus and pain. Nerve injury induces ephaptic transmission and ectopic excitation. The physiopathological mechanisms of this type of myoclonus involve a peripheral generator that induces central (spinal) generator activity. © 2008 Movement Disorder Society
Url:
DOI: 10.1002/mds.21998
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000E12
- to stream Istex, to step Curation: 000E12
- to stream Istex, to step Checkpoint: 000D97
- to stream PubMed, to step Corpus: 001F07
- to stream PubMed, to step Curation: 001F07
- to stream PubMed, to step Checkpoint: 001D02
- to stream Ncbi, to step Merge: 002458
- to stream Ncbi, to step Curation: 002458
- to stream Ncbi, to step Checkpoint: 002458
- to stream Main, to step Merge: 002A56
- to stream PascalFrancis, to step Corpus: 000F83
- to stream PascalFrancis, to step Curation: 001D36
- to stream PascalFrancis, to step Checkpoint: 000D96
- to stream Main, to step Merge: 002E93
- to stream Main, to step Curation: 002195
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Myoclonus of peripheral origin: Two case reports</title><author><name sortKey="Tyvaert, Louise" sort="Tyvaert, Louise" uniqKey="Tyvaert L" first="Louise" last="Tyvaert">Louise Tyvaert</name></author><author><name sortKey="Krystkowiak, Pierre" sort="Krystkowiak, Pierre" uniqKey="Krystkowiak P" first="Pierre" last="Krystkowiak">Pierre Krystkowiak</name></author><author><name sortKey="Cassim, Francois" sort="Cassim, Francois" uniqKey="Cassim F" first="Francois" last="Cassim">Francois Cassim</name></author><author><name sortKey="Houdayer, Elise" sort="Houdayer, Elise" uniqKey="Houdayer E" first="Elise" last="Houdayer">Elise Houdayer</name></author><author><name sortKey="Kreisler, Alexandre" sort="Kreisler, Alexandre" uniqKey="Kreisler A" first="Alexandre" last="Kreisler">Alexandre Kreisler</name></author><author><name sortKey="Destee, Alain" sort="Destee, Alain" uniqKey="Destee A" first="Alain" last="Destée">Alain Destée</name><affiliation><country>France</country><placeName><settlement type="city">Lille</settlement><region type="region" nuts="2">Nord-Pas-de-Calais</region></placeName><orgName type="university" n="3">Université Lille 2</orgName><orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName></affiliation></author><author><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name><affiliation><country>France</country><placeName><settlement type="city">Lille</settlement><region type="region" nuts="2">Nord-Pas-de-Calais</region></placeName><orgName type="university" n="3">Université Lille 2</orgName><orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:5080EA9C3532425C8D36639145DEADC853AA1DE2</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1002/mds.21998</idno><idno type="url">https://api.istex.fr/document/5080EA9C3532425C8D36639145DEADC853AA1DE2/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000E12</idno><idno type="wicri:Area/Istex/Curation">000E12</idno><idno type="wicri:Area/Istex/Checkpoint">000D97</idno><idno type="wicri:doubleKey">0885-3185:2009:Tyvaert L:myoclonus:of:peripheral</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:19086086</idno><idno type="wicri:Area/PubMed/Corpus">001F07</idno><idno type="wicri:Area/PubMed/Curation">001F07</idno><idno type="wicri:Area/PubMed/Checkpoint">001D02</idno><idno type="wicri:Area/Ncbi/Merge">002458</idno><idno type="wicri:Area/Ncbi/Curation">002458</idno><idno type="wicri:Area/Ncbi/Checkpoint">002458</idno><idno type="wicri:Area/Main/Merge">002A56</idno><idno type="wicri:source">INIST</idno><idno type="RBID">Pascal:09-0104581</idno><idno type="wicri:Area/PascalFrancis/Corpus">000F83</idno><idno type="wicri:Area/PascalFrancis/Curation">001D36</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000D96</idno><idno type="wicri:doubleKey">0885-3185:2009:Tyvaert L:myoclonus:of:peripheral</idno><idno type="wicri:Area/Main/Merge">002E93</idno><idno type="wicri:Area/Main/Curation">002195</idno><idno type="wicri:Area/Main/Exploration">002195</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Myoclonus of peripheral origin: Two case reports</title><author><name sortKey="Tyvaert, Louise" sort="Tyvaert, Louise" uniqKey="Tyvaert L" first="Louise" last="Tyvaert">Louise Tyvaert</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology and Movement Disorders, Lille University Hospital, Lille Cedex</wicri:regionArea><wicri:noRegion>Lille Cedex</wicri:noRegion><wicri:noRegion>Lille Cedex</wicri:noRegion></affiliation></author><author><name sortKey="Krystkowiak, Pierre" sort="Krystkowiak, Pierre" uniqKey="Krystkowiak P" first="Pierre" last="Krystkowiak">Pierre Krystkowiak</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology and Movement Disorders, Lille University Hospital, Lille Cedex</wicri:regionArea><wicri:noRegion>Lille Cedex</wicri:noRegion><wicri:noRegion>Lille Cedex</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology, North Hospital Amiens University, Amiens Cedex, France; 3Department of Clinical Neurophysiology, Lille University Hospital, Lille Cedex</wicri:regionArea><wicri:noRegion>Lille Cedex</wicri:noRegion><wicri:noRegion>Lille Cedex</wicri:noRegion></affiliation></author><author><name sortKey="Cassim, Francois" sort="Cassim, Francois" uniqKey="Cassim F" first="Francois" last="Cassim">Francois Cassim</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology, North Hospital Amiens University, Amiens Cedex, France; 3Department of Clinical Neurophysiology, Lille University Hospital, Lille Cedex</wicri:regionArea><wicri:noRegion>Lille Cedex</wicri:noRegion><wicri:noRegion>Lille Cedex</wicri:noRegion></affiliation></author><author><name sortKey="Houdayer, Elise" sort="Houdayer, Elise" uniqKey="Houdayer E" first="Elise" last="Houdayer">Elise Houdayer</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology, North Hospital Amiens University, Amiens Cedex, France; 3Department of Clinical Neurophysiology, Lille University Hospital, Lille Cedex</wicri:regionArea><wicri:noRegion>Lille Cedex</wicri:noRegion><wicri:noRegion>Lille Cedex</wicri:noRegion></affiliation></author><author><name sortKey="Kreisler, Alexandre" sort="Kreisler, Alexandre" uniqKey="Kreisler A" first="Alexandre" last="Kreisler">Alexandre Kreisler</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology and Movement Disorders, Lille University Hospital, Lille Cedex</wicri:regionArea><wicri:noRegion>Lille Cedex</wicri:noRegion><wicri:noRegion>Lille Cedex</wicri:noRegion></affiliation></author><author><name sortKey="Destee, Alain" sort="Destee, Alain" uniqKey="Destee A" first="Alain" last="Destée">Alain Destée</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology and Movement Disorders, Lille University Hospital, Lille Cedex</wicri:regionArea><wicri:noRegion>Lille Cedex</wicri:noRegion><wicri:noRegion>Lille Cedex</wicri:noRegion><placeName><settlement type="city">Lille</settlement><region type="region" nuts="2">Nord-Pas-de-Calais</region></placeName><orgName type="university" n="3">Université Lille 2</orgName><orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName></affiliation></author><author><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology and Movement Disorders, Lille University Hospital, Lille Cedex</wicri:regionArea><wicri:noRegion>Lille Cedex</wicri:noRegion><wicri:noRegion>Lille Cedex</wicri:noRegion><placeName><settlement type="city">Lille</settlement><region type="region" nuts="2">Nord-Pas-de-Calais</region></placeName><orgName type="university" n="3">Université Lille 2</orgName><orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-01-30">2009-01-30</date><biblScope unit="vol">24</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="274">274</biblScope><biblScope unit="page" to="277">277</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">5080EA9C3532425C8D36639145DEADC853AA1DE2</idno><idno type="DOI">10.1002/mds.21998</idno><idno type="ArticleID">MDS21998</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Amputation Stumps (physiopathology)</term><term>Anterior Horn Cells (physiology)</term><term>Anti-Dyskinesia Agents (therapeutic use)</term><term>Arm Injuries (surgery)</term><term>Botulinum Toxins, Type A (therapeutic use)</term><term>Brachial Plexus (injuries)</term><term>Brachial Plexus (physiopathology)</term><term>Case study</term><term>Cervical Vertebrae</term><term>Cicatrix (physiopathology)</term><term>Elbow (injuries)</term><term>Electromyography</term><term>Female</term><term>Humans</term><term>Lidocaine (therapeutic use)</term><term>Male</term><term>Middle Aged</term><term>Myoclonus</term><term>Myoclonus (drug therapy)</term><term>Myoclonus (etiology)</term><term>Nervous system diseases</term><term>Neural Conduction</term><term>Pain</term><term>Paresthesia (etiology)</term><term>Phantom Limb (complications)</term><term>Phantom limb</term><term>Physical Stimulation (adverse effects)</term><term>Spinal Osteophytosis (complications)</term><term>Ulnar Nerve (injuries)</term><term>Ulnar Nerve (physiopathology)</term><term>nerve injury</term><term>peripheral myoclonus</term><term>phantom‐limb pain</term><term>spinal myoclonus</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Dyskinesia Agents</term><term>Botulinum Toxins, Type A</term><term>Lidocaine</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Physical Stimulation</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Phantom Limb</term><term>Spinal Osteophytosis</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Myoclonus</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Myoclonus</term><term>Paresthesia</term></keywords><keywords scheme="MESH" qualifier="injuries" xml:lang="en"><term>Brachial Plexus</term><term>Elbow</term><term>Ulnar Nerve</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Anterior Horn Cells</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Amputation Stumps</term><term>Brachial Plexus</term><term>Cicatrix</term><term>Ulnar Nerve</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Arm Injuries</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Cervical Vertebrae</term><term>Electromyography</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neural Conduction</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Douleur</term><term>Etude cas</term><term>Membre fantôme</term><term>Myoclonie</term><term>Pathologie du système nerveux</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The concept of peripheral myoclonus is not yet fully accepted by the medical community because of the difficulty in establishing a cause‐and‐effect relationship between trauma and subsequent movement disorders. Here, we report two cases of patients suffering from peripheral myoclonus after nerve injury. The first patient experienced myoclonus of the 4th dorsal interosseous muscle several days after trauma to the elbow. The second patient presented myoclonus of the arm stump (combined with phantom‐limb pain) 1 year after amputation. In both cases, central nervous system function (spine and brain imaging, somesthetic evoked potentials, EEG back‐averaging) was normal. For the second patient, local infiltration of xylocaine and botulinum toxin into the stump scar rapidly stopped myoclonus and pain. Nerve injury induces ephaptic transmission and ectopic excitation. The physiopathological mechanisms of this type of myoclonus involve a peripheral generator that induces central (spinal) generator activity. © 2008 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Nord-Pas-de-Calais</li></region><settlement><li>Lille</li></settlement><orgName><li>Université Lille 2</li><li>Université Lille Nord de France</li></orgName></list><tree><country name="France"><noRegion><name sortKey="Tyvaert, Louise" sort="Tyvaert, Louise" uniqKey="Tyvaert L" first="Louise" last="Tyvaert">Louise Tyvaert</name></noRegion><name sortKey="Cassim, Francois" sort="Cassim, Francois" uniqKey="Cassim F" first="Francois" last="Cassim">Francois Cassim</name><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name><name sortKey="Destee, Alain" sort="Destee, Alain" uniqKey="Destee A" first="Alain" last="Destée">Alain Destée</name><name sortKey="Houdayer, Elise" sort="Houdayer, Elise" uniqKey="Houdayer E" first="Elise" last="Houdayer">Elise Houdayer</name><name sortKey="Kreisler, Alexandre" sort="Kreisler, Alexandre" uniqKey="Kreisler A" first="Alexandre" last="Kreisler">Alexandre Kreisler</name><name sortKey="Krystkowiak, Pierre" sort="Krystkowiak, Pierre" uniqKey="Krystkowiak P" first="Pierre" last="Krystkowiak">Pierre Krystkowiak</name><name sortKey="Krystkowiak, Pierre" sort="Krystkowiak, Pierre" uniqKey="Krystkowiak P" first="Pierre" last="Krystkowiak">Pierre Krystkowiak</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002195 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002195 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:5080EA9C3532425C8D36639145DEADC853AA1DE2
|texte= Myoclonus of peripheral origin: Two case reports
}}
| This area was generated with Dilib version V0.6.23. |  |